Characteristic | Supratentorial PNET | Medulloblastoma |
Prevalence | <2% pediatric CNS tumors | ~20% pediatric CNS tumors |
Mean age at presentation | 3 years | 5 years |
Sex | Equal incidence | Males>females |
Imaging | Heterogeneous enhancement
Distinct border Poorly differentiated |
Homogeneous enhancement |
Histopathology | Neuroepithelial cells
Small round nuclei |
Same |
Molecular biology | No specific chromosomal abnormalities | 17p deletion
17q addition |
Metastasis | 5 – 39% | 40 – 60% |
Treatment | Surgery
Craniospinal XRT Chemotherapy |
Same |
3-year progression-free survival | 45 – 49% | >80% |
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