Radiation Therapy
- 75–80% 5-year event-free survival with conservative surgery followed by radiation: This rate is the cited experience in papers published between 1992 and 2000 (2, 32, 42, 46).
- 71% (17/22) 10-year event-free survival with surgery followed by radiation: This rate was reported in one study of children treated with surgery followed by radiation, and 75% (18/22) were alive at 10 years. Four had experienced second malignancies, and another two had late occurrence of anaplastic astrocytomas (37).
- Anaplastic IMSCTs and recurrent low-grade IMSCTs: For these tumors in older children and adolescents, there is consensus for the use of radiation therapy (34).
Chemotherapy
- Little information available: Reports on the use of chemotherapy for benign IMSCTs are largely case reports or very small series.
- Reports difficult to interpret: The studies that are available are difficult to interpret, given the indolent nature of these tumors, the short follow-up of the studies, and the small number of children in studies.
Please create a free account or log in to read 'Adjuvant Therapies for Intramedullary Spinal Cord Tumors in Children'
The ISPN Guide and ISPN Library are one platform. Register once and complete your profile to access both resources.
