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Supratentorial Ependymomas in Children Homepage

This page was last updated on January 3rd, 2023

Author

Keith Goh, MBBS, FRCSEd, FCSHK, FHKAM, FAMS

Section Editor

Kristian Aquilina, M.D.

Editor in Chief

Rick Abbott, M.D.

Introduction

Ependymomas are gliomas that comprise about 9% of all intracranial tumors in children. They are the third most common tumor after astrocytomas and primitive neuroectodermal tumors. Two-thirds of intracranial ependymomas occur in the infratentorial compartment, while one-third are supratentorial. Supratentorial ependymomas are usually intraparenchymal tumors that have cystic components and can be very large at diagnosis.

Key Points

  • Large tumors: These tumors reach large sizes with a cystic component, and they often have increased vascularity.
  • Extent of surgery predicts survival: The completeness of resection is the most important prognostic factor. Therefore, the goal of treatment is a gross total resection, where possible.
  • Post-resection radiation recommended: Adjuvant treatment with radiotherapy is recommended in most cases.

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