| Characteristic | Supratentorial PNET | Medulloblastoma |
| Prevalence | <2% pediatric CNS tumors | ~20% pediatric CNS tumors |
| Mean age at presentation | 3 years | 5 years |
| Sex | Equal incidence | Males>females |
| Imaging | Heterogeneous enhancement Distinct border Poorly differentiated | Homogeneous enhancement |
| Histopathology | Neuroepithelial cells Small round nuclei | Same |
| Molecular biology | No specific chromosomal abnormalities | 17p deletion 17q addition |
| Metastasis | 5 – 39% | 40 – 60% |
| Treatment | Surgery Craniospinal XRT Chemotherapy | Same |
| 3-year progression-free survival | 45 – 49% | >80% |
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