Tap on and choose 'Add to Home Screen' to create a shortcut app

Tap on and choose 'Add to Home Screen/Install App' to create a shortcut app

Differences Between Supratentorial PNET and Medulloblastoma (Infratentorial PNET) in Children

This page was last updated on May 17th, 2017

Characteristic Supratentorial PNET Medulloblastoma
Prevalence <2% pediatric CNS tumors ~20% pediatric CNS tumors
Mean age at presentation 3 years 5 years
Sex Equal incidence Males>females
Imaging Heterogeneous enhancement

Distinct border

Poorly differentiated

Homogeneous enhancement
Histopathology Neuroepithelial cells

Small round nuclei

Molecular biology No specific chromosomal abnormalities 17p deletion

17q addition

Metastasis 5 – 39% 40 – 60%
Treatment Surgery

Craniospinal XRT


3-year progression-free survival 45 – 49% >80%

Your donations keep us going

The ISPN Guide is free to use, but we rely on donations to fund our ongoing work and to maintain more than a thousand pages of information created to disseminate the most up-to-date knowledge in the field of paediatric neurosurgery.

By making a donation to The ISPN Guide you are also indirectly helping the many thousands of children around the world whose treatment depends on well-informed surgeons.

Please consider making a donation today.

Use the app

The ISPN Guide can be used as a standalone app, both on mobile devices and desktop computers. It’s quick and easy to use.

Fully featured

Free registration grants you full access to The Guide and host of featured designed to help further your own education.

Stay updated

The ISPN Guide continues to expand both in breadth and depth. Join our mailing list to stay up-to-date with our progress.