Tap on and choose 'Add to Home Screen' to create a shortcut app

Tap on and choose 'Add to Home Screen/Install App' to create a shortcut app

Complications of Therapy for Supratentorial Primitive Neuroectodermal Tumors in Children

This page was last updated on May 9th, 2017


  • Hydrocephalus



  • Function of age: The age below which the risks associated with radiotherapy become unacceptable is unknown. Most oncologists use 3 years of age as the lower limit, but others have suggested that craniospinal irradiation should not be considered in children below 5 years of age (15).
  • Site and dose dependent: The drawbacks to radiotherapy in children are the well-known, long-term sequelae. Depending on the portion of the CNS that is irradiated, the specific dosing regimen, and, particularly, the age at initiation of radiotherapy, the child who receives craniospinal irradiation is potentially at risk of radiation necrosis, neuroendocrinopathies, and cognitive impairments.

Your donations keep us going

The ISPN Guide is free to use, but we rely on donations to fund our ongoing work and to maintain more than a thousand pages of information created to disseminate the most up-to-date knowledge in the field of paediatric neurosurgery.

By making a donation to The ISPN Guide you are also indirectly helping the many thousands of children around the world whose treatment depends on well-informed surgeons.

Please consider making a donation today.

Use the app

The ISPN Guide can be used as a standalone app, both on mobile devices and desktop computers. It’s quick and easy to use.

Fully featured

Free registration grants you full access to The Guide and host of featured designed to help further your own education.

Stay updated

The ISPN Guide continues to expand both in breadth and depth. Join our mailing list to stay up-to-date with our progress.