Cite

Copy

Tap on and choose 'Add to Home Screen' to create a shortcut app

Tap on and choose 'Install/Install App' to create a shortcut app

Management of Supratentorial Choroid Plexus Tumors in Children

This page was last updated on May 9th, 2017

Initial Management at Presentation

  • Control of hydrocephalus: Emergent management of hydrocephalus may be required if the child is lethargic from elevated ICP related to hydrocephalus. EVD placement may be required prior to definitive resection of the tumor.
  • Embolization: Preoperative embolization is useful in reducing the amount of blood loss during the surgical resection. However, since 75% of these tumors are diagnosed in children younger than 2 years of age, there are technical difficulties linked to embolization, and the risks vs. benefits might differ depending on the experience of the interventional team.
  • Surgical resection: For choroid plexus papillomas, total surgical resection leads to a cure in a large percentage of cases and therefore should be the aim. For choroid plexus carcinomas, gross total resection also leads to better outcomes.

Adjunctive Therapies

Choroid plexus carcinoma

  • Chemotherapy: The role of adjuvant chemotherapy is controversial. It can be used in young children when deferring radiation treatment. Use of a combination of ifosfamide, carboplatin, and etoposide (ICE) has been described (111).
  • Radiotherapy: As many as 44% of carcinomas will have CSF seeding. Radiotherapy is indicated with a positive neuraxis staging, a WHO grade III, and positive margins. However, radiation treatment will be deferred in children younger than 3 or 4 years of age (111).

Follow-up

  • Scheduled follow-up: Typically, early follow-up is planned for 4–6 weeks after surgery.
  • Postoperative imaging important: The first postoperative imaging should be done within 72 hours to make sure there is no residual tumor or to assess its size if tumor remains. Follow-up imaging will then depend on the pathology of the tumor and on the adjuvant therapies (typically every 3 months for choroid plexus carcinomas; and every 6 months, then every year for choroid plexus papillomas).

Your donations keep us going

The ISPN Guide is free to use, but we rely on donations to fund our ongoing work and to maintain more than a thousand pages of information created to disseminate the most up-to-date knowledge in the field of paediatric neurosurgery.

By making a donation to The ISPN Guide you are also indirectly helping the many thousands of children around the world whose treatment depends on well-informed surgeons.

Please consider making a donation today.

Use the app

The ISPN Guide can be used as a standalone app, both on mobile devices and desktop computers. It’s quick and easy to use.

Fully featured

Free registration grants you full access to The Guide and host of featured designed to help further your own education.

Stay updated

The ISPN Guide continues to expand both in breadth and depth. Join our mailing list to stay up-to-date with our progress.