Tap on and choose 'Add to Home Screen' to create a shortcut app

Tap on and choose 'Add to Home Screen/Install App' to create a shortcut app

Presentation of Supratentorial Pleomorphic Xanthoastrocytomas in Children

This page was last updated on May 9th, 2017


  • Seizures most common symptom: Seizures are the most common presenting symptom, usually long-lasting seizures that were not investigated by imaging at their onset.
  • Occasionally, symptoms due to elevated ICP: Less frequently, patients may develop intracranial hypertension.
  • Focal neurological deficits unusual 

Patterns of evolution

  • Seizures: Because seizures usually are the first presenting symptom, the tumor is most often diagnosed with imaging following seizures.

Time for evolution

  • Slow: Usually PXAs are slow-growing tumors unless the tumor is an anaplastic variant.

Intervention at Presentation


  • Seizure: Antiseizure medication is used to manage the presenting complaint.

Preparation for definitive intervention, nonemergent

  • Imaging: MRI should be done.
  • Plan surgery: After imaging, a surgical approach can be chosen and the case discussed with the parents. Surgery can be done as a semi-elective case in the OR.

Preparation for definitive intervention, emergent

  • Manage hydrocephalus: In rare cases, if the tumor is large enough or causes hydrocephalus by blocking CSF pathways, then hydrocephalus has to be dealt with (i.e., EVD or direct removal of the tumor).
  • Imaging: Imaging should be done. If the child’s condition is unstable, a CT scan will suffice to assess the pathology and the hydrocephalus.

Admission Orders

  • Routine: Standard admission orders are used in preparing the child for surgery.

Your donations keep us going

The ISPN Guide is free to use, but we rely on donations to fund our ongoing work and to maintain more than a thousand pages of information created to disseminate the most up-to-date knowledge in the field of paediatric neurosurgery.

By making a donation to The ISPN Guide you are also indirectly helping the many thousands of children around the world whose treatment depends on well-informed surgeons.

Please consider making a donation today.

Use the app

The ISPN Guide can be used as a standalone app, both on mobile devices and desktop computers. It’s quick and easy to use.

Fully featured

Free registration grants you full access to The Guide and host of featured designed to help further your own education.

Stay updated

The ISPN Guide continues to expand both in breadth and depth. Join our mailing list to stay up-to-date with our progress.