| Age | Pathogens | |
| Neonate (118) | Proteus Citrobacter Enterobacter | |
| Child (55, 132) | Streptococcus (aerobic and anaerobic) 60-70% Gram negative anaerobic 20-40% Enterobacter Staphylococcus 10-15% | |
| Route of Infection | Condition | Pathogens |
| Hematogenous | ||
| Congenital heart disease | Streptococcus viridans Staphylococcus aureus Streptococcus (aerobic and microaerophillic) Haemophilus sp. | |
| Endocarditis | Staphylococcus aureus Streptococcus (aerobic and microaerophillic) | |
| Bacteremia | Staphylococcus aureus Streptococcus (aerobic and microaerophillic) Gram negative anaerobic bacilli | |
| Pulmonary infection | Streptococcus (aerobic and anaerobic) Nocardia Gram negative anaerobic bacilli Fusobacterium Actinomyces | |
| Skin folliculitis | Staphylococcus aureus Streptococcus | |
| Osteomyelitis | Staphylococcus aureus Enterobacter Streptococcus Haemophilus sp. | |
| Pulmonary foreign body (aspiration) | Streptococcus (aerobic and anaerobic) Gram negative anaerobic bacilli Nocardia Fusobacterium Actinomyces | |
| Contiguous | ||
| Otitis media | Streptococcus (aerobic and anaerobic) Enterobacter Pseudomonas Provetella Bacteroides | |
| Sinus infection | Streptococcus (aerobic and anaerobic) Enterobacter Pseudomonas Fusobacterium Bacteroides Haemophilus sp. | |
| Meningitis | Staphylococcus Gram negative bacilli Streptococcus Listeria Haemophilus sp. | |
| Dental infection | Mixed anaerobes Streptococcus (aerobic and anaerobic) Staphylococcus aureus Enterococcus | |
| Trauma | ||
| Penetrating cranial injury | Streptococcus Staphylococcus Enterococcus Mycobacterium Bacteroides Clostridium | |
| Neurosurgical procedure | Staphylococcus Pseudomonas Enterococcus | |
| Immunological Status | Pathogens | |
| Immunocompromised | Nocardia Mycobacteria (TB) Gram negative anaerobic bacilli Asperillus Candida Enterobacter Cryptococcus Toxoplasma gondii Mucorales Listeria |
(Adapted from 31, 51)
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