Incidence
- Medulloblastomas are the most common malignant pediatric brain tumor, accounting for 15–20% of pediatric brain tumors and 30–55% of posterior fossa tumors (13, 19, 20).
Age Distribution
- The mean age at presentation is 5–7 years, and 80% of patients are younger than 15 years (13).
Sex Predilection
- Medulloblastomas are more common in males than females, with the male:female ratio ranging from 1.4:1 to greater than 2:1, depending on the series (3, 8).
Geographic Distribution
- None known
Risk Factors
- None known: No environmental factors have been definitively associated with medulloblastoma incidence (15).
Relationships to Other Disease States and Syndromes
- Gorlin’s syndrome: 5% incidence of medulloblastoma, also associated with multiple nevoid and basal cell carcinomas, multiple skeletal and cutaneous anomalies, hydrocephalus, calcification of the dura, and developmental delay (15).
- Turcot’s syndrome: Known also as multiple familia polyposis, associated with colorectal polyps and colorectal carcinoma (15).
Please create a free account or log in to read 'Epidemiology of Medulloblastomas in Children'
The ISPN Guide and ISPN Library are one platform. Register once and complete your profile to access both resources.
