Glossary

Tenecteplase. Tenecteplase is a modified form of a plasminogen activator (enzyme which dissolves blood clots) used in the emergency treatment of myocardial infarction and pulmonary emboli.

Time-of-flight magnetic resonance angiography: A MRI technique for imaging flow within blood vessels and, consequently, the anatomy of blood vessels without the use fo contrasting agent.  It is based on the principle of repeated application of magnetic pulses followed by a recording of signals emitted by protons as they “relax” out of the state induced by the magnetic pulse.  Since blood flowing within vessels in the field being imaged brings fresh protons to area the summation of recordings after repeated magnetic stimulation shows the increasing volume of signal due fresh protons within the blood as oppose to the lower signal summation in surrounding tissue where fresh protons are not being introduced between magnetic pulses.

An acronym describing a group of infections effecting infant during the perinatal period. It stands for Toxoplasmosis, Other, Rubella, Cytomegalovirus and Herpes Simplex Virus,

Tissue plasminogen activator – an enzyme that catalyzes the breakdown of blood clots by driving the conversion of plasminogen to plasmin.

A process which inhibits or prevents transcription of DNA. Transcriptional repressor proteins can achieve this by either counteracting positively acting transcriptional factors or inhibiting the basic transcriptional machinery.

– also know as trepination. Derived from the Greek trypanon – a borer. This refers to making a hole, by drilling or scrapping, through the skull or other body surface. It is typically done as part of a therapeutic technique where the dura is exposed to allow for a intracranial treatment such as relieving pressure or draining fluid.

– also know as trepanation, the preferred use. This refers to making a hole, by drilling or scrapping, through the skull or other body surface. It is typically done as part of a therapeutic technique where the dura is exposed to allow for a intracranial treatment such as relieving pressure or draining fluid.

The Superior Anastomotic Vein.  It anastomoses with the Middle Cerebral Vein and the Sagittal Sinus.

Tuberous sclerosis or tuberous sclerosis complex.

Tuberous sclerosis complex – a rare multi-system disease associated with benign tumors in the brain, kidneys, heart, eyes, lungs and skin. Problems that can be seen in this condition include seizures, developmental delay, poorly controlled behavior, skin abnormalities , lung and kidney disease. The disease is heritable.