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Zülch Classification of Brain Tumors

This page was last updated on April 8th, 2024

The application of the Zülch classification system to childhood brain tumors was criticized because it did not differentiate the cellular polymorphism common in childhood tumors from that occurring in adult CNS tumors. Furthermore, it did not specify location as a prognostic criterion, and it considered a tumor as benign or malignant instead of using the term anaplasia. Lastly, it used the term “poorly differentiated” for certain tumor types that neuropathologists felt should have been called “primitive” because of their histogenesis.

CategoriesSubcategories
Neuroepithelial tumors 
 Medulloblastomas
 Gliomas
 Paragliomas
 Gangliocytomas
Mesodermal tumors 
Ectodermal tumors 
Congenital and embryonic tumors 
Vascular malformations and blood vessel tumors 
Other space-occupying processes 

Adapted from Zülch (28)

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